It’s not unusual for a John or two to turn up dead on Hooker street. But when bodies start piling up by the dozens, each drained of blood and sharing the same neck wounds, people start to notice. Among those people is Vanessa Helsing, professor of mystical studies at the local college. After some gratuitous exposition establishing that Vanessa is brilliant and badass but thought of as a joke by her colleagues, she pieces together that the murderesses are a band of vampire hookers, and the only way to stop them is to kill the head vampire- their smooth-talking vampire pimp. It’s up to Vanessa and her group of ass-kicking grad students to stop these tricks that are not worth the treat.