Betty is young bilingual nerd adjusting to college and life away from her traditional family in a southern Texas town. The all-too-easy target of mean-spirited practical jokes, her college-assigned WASPy roommates enter her profile on a campus dating website- complete with phony pictures and background- hoping to get a few giggles out of her embarrassment. But their plan backfires when Juan, the victim of an identical prank by his own new cruel roommates, answers the add. The tables are turned when the new fugly-pair team up to even the score for themselves and all fugly-kind.